I will make just one more rebuttal and then drop this..
Rebuilding the Injector will help with the atomization and proper modulation of fuel into your cylinder. Will also take care of any carbon build up and prevent failure due to being worn out. I have seen studies that state it is a good idea to do. If you do a cost advantage study and rebuilding your injectors makes a half mile per gallon difference at 100,000 miles and maybe a whole gpm at 200,000 miles is it cost effective to change it out? Or just wait until you have hard starts... Is it necessary to do? No, you can wait until your injectors start failing and maybe hope that injector cleaner does something... Have I changed out the injectors in my truck? At 240,000 miles? No.. I will likely do so in the next year however.. It just wasn't a high priority with the other stuff I am doing.
O2 sensors... Do they have to be replaced? No.. You can wait for them to fully fail (And for the secondary O2 sensors I wouldn't change them unless they do fully fail.) They have been shown to become more erratic after a certain point and your fuel efficiency will suffer. We could be talking as little as a half mile per gallon or 2-3 or more miles to the gallon. This again is a cost evaluation.. You CAN run with bad O2 sensors although it can drastically reduce your cats lifespan. The secondary O2 sensors do nothing but warn of a possible cat issue and can be disabled with no ill effects. Front sensors can directly effect your fuel mileage as much as any other sensor.
Plugs, Wires... These wear out at a much faster rate and have a plan failure rate. You should replace at the worst every 100,000 miles. These are very cheap and to maintain best efficiency you should change platnum plugs sometime between 50,000 and 100,000 miles. Every additional mile you get out of them is that much less you need to have the next set in for but as I have previously mentioned I have seen a couple different studies that stated at 50,000 miles your plugs show a measurable wear. 100,000 miles is if your lucky...
The time to change is like an oil change or anything else.. It is an estimated guess based on the mean failure rate of the component. You could easily get 200,000 miles out of a set of plugs and never have an issue. You might get 100,000 miles out of an air filter too. But an air filter you can actually inspect. A plug you can inspect as well. Things like O2 sensors or injectors you really can't inspect unless you do it under lab conditions and have a special tester to test them against others.
The main point of Preventative maintenance is to replace components you know will wear out or go bad before they do. The art to them is to know based on their age and possibly condition when the best time to do that without wasting life of that component. Corrective maintenance is fixing something that is already broken. Personally I tend to like to change stuff out that is showing signs of wearing out before it actually breaks causing other issues or other things to break. But you can do as some do and never fix anything and just sell your vehicle when the list of repairs is long and you don't want to deal with them knowing you will have to spend a lot of time and money all at once or junk it. It is totally ones own choice.
I only mentioned the things I did because if you want your truck to run optimally you really should take a good look at these items as replace items. No different than changing out the Knock sensors and harness when someone had an intake leak... You KNOW its going to be an issue so take care of it before it is...
Rodney